Moreover, es cell differentiation in vitro recapitulates events that take place. Affymetrix 1999 genechip expression analysis technical m. Research into the reprogramming of somatic cells into pluripotent stem cells received the nobel prize in 2012. This stem cells animation explains about stem cell therapy. B cell activation and plasma cell differentiation immunopaedia. As a class, students view animations to learn about how the microenvironment contributes to the differentiation of adult stem cells. This animation is a clip from a 2006 holiday lecture series, potent biology. Immune system must create a repertoire of receptors capable. Nova online teachers classroom activity nova sciencenow. Differentiation and the fate of cells hhmi biointeractive.
Stem cell differentiation and the microenvironment californias. Both of these processes are fundamentally controlled by the cell signaling mechanisms discussed in the previous lesson, and are the focus of this lesson. In a later stage of development called the gastrula, the cells differentiate to form three germ layers. Updated each month, this curated list of articles includes content from all three cddpress titles. Slide 3 when you started out as a zygote it would be fair to say that you, as a. Bcell development, activation, and differentiation roswell park. By viewing animations lacking narration and coming up with explanations. Use interactive, animated activities to identify the living and. T cells also provide cytokines to b cells that support their survival il4, differentiation into plasma cells il21 or class switch recombination. An animation to illustrate how cells are removed from the inner cell mass and. An analysis of the concept of plasticity in the context. Cell differentiation accessscience from mcgrawhill education. Illustrates how coaxing agents can be used to control stem cell differentiation.
Each layer gives rise to specific tissues with increasingly specialized cells. Immature b cell leaves the bone marrow and undergoes further differentiation. All cells in the human body originate from a group of embryonic stem cells called the inner cell mass icm, which is. The mechanism by which cells in a multicellular organism become specialized to perform specific functions in a variety of tissues and organs. The important properties of stem cells are explained with this animation taken from university of. Use the stem cells to grow specialized cells with faulty genes, e. Germinal center cell differentiation into plasma cells 515 days after initial antigen exposure, a portion of the germinal center b cells will upregulate irf 4 critical for plasma cell differentiation irf4 knockout mice lack ig secreting plasma cells irf4 overexpression promotes plasma cell differentiation. Follow the url to the website and watch the animation on.
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